For laboratory research use only · Not for human consumption

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lot ABL-MOT-2601
≥99% HPLC · RUO

Metabolic

MOTS-c

Mitochondrial-derived peptide · Metabolic research

A 16-amino-acid peptide encoded within the mitochondrial 12S rRNA region, studied as a metabolic signaling molecule and modulator of AMPK-dependent pathways.


For laboratory research use only. Not for human or animal consumption, not a drug, food, cosmetic, or supplement. By adding to cart, the researcher affirms compliance with all applicable regulations.

Vial size

Research price

$89

SKU ABL-MOT-5

Ships cold-chain · Lot ABL-MOT-2601 · Checkout secured by Waave

Specifications

CAS number
1627580-64-6
Molecular formula
C100H162N28O25S
Molecular weight
2174.6 g/mol
Sequence
MRWQEMGYIFYPRKLR
Purity (HPLC)
≥99%
Appearance
White lyophilized powder
Storage
Store lyophilized at −20 °C, protected from light and moisture
Reconstitution
Reconstitute in sterile diluent appropriate to researcher protocol
Latest lot
ABL-MOT-2601

MOTS-c (Mitochondrial ORF of the Twelve S rRNA-c) is one of a small family of peptides encoded within the mitochondrial genome. Since its characterization by the Cohen group, published research has examined its role as a mitochondrial-derived signaling peptide influencing insulin sensitivity, AMPK activation, and metabolic homeostasis in preclinical models.

Studies have reported MOTS-c effects on glucose uptake in skeletal muscle, age-associated metabolic decline, and exercise-related metabolic adaptation.

The peptide is supplied as a research tool for investigation of mitochondrial signaling and the emerging field of mitochondrial-derived peptide biology.