For laboratory research use only · Not for human consumption

Axis Bio.
Back to catalog
lot ABL-RET-2601
≥99% HPLC · RUO

Metabolic

Retatrutide

LY3437943

Triple GIP / GLP-1 / glucagon receptor agonist

A next-generation synthetic peptide engineered as a unimolecular triple agonist at the GIP, GLP-1, and glucagon receptors. Actively studied in Phase 2/3 trials and an object of intense research interest.


For laboratory research use only. Not for human or animal consumption, not a drug, food, cosmetic, or supplement. By adding to cart, the researcher affirms compliance with all applicable regulations.

Vial size

Research price

$269

SKU ABL-RET-5

Ships cold-chain · Lot ABL-RET-2601 · Checkout secured by Waave

Specifications

CAS number
2381089-83-2
Molecular formula
C221H343N51O64
Molecular weight
4731.37 g/mol
Sequence
YXQGTFTSDYSIYLDKKAQXAFIEYLLEGGPSSGAPPPS (Aib substitutions; C20 diacid)
Purity (HPLC)
≥99%
Appearance
White lyophilized powder
Storage
Store lyophilized at 2–8 °C, protected from light and moisture
Reconstitution
Reconstitute in sterile diluent appropriate to researcher protocol
Latest lot
ABL-RET-2601

Retatrutide is a synthetic peptide engineered as a balanced agonist at three metabolic receptors simultaneously: GIP, GLP-1, and glucagon. The molecule represents a significant step in the evolution of incretin-based research tools, extending the dual-agonist concept of Tirzepatide with an added glucagon component intended to engage hepatic and thermogenic pathways.

Published Phase 2 literature has reported substantial effects on body weight, hepatic fat, and glycemic endpoints in study populations with obesity and type 2 diabetes. Phase 3 programs are ongoing as of the most recent publications.

Supplied as a research-grade reference peptide for investigation of triple-agonist incretin pharmacology. Not supplied for therapeutic use.